Adrian Grenier; Niecy Nash; guest co-host Chelsea Handler (S12E1)
9/8/2008
Nastia Liukin; Meghan McCain; Judge Judy Sheindlin (S12E2)
9/9/2008
Jamie Lee Curtis, Natalie Cole (S12E3)
9/10/2008
Jessica Simpson; Tyler Perry (S12E4)
9/11/2008
John McCain and Cindy Hensley McCain (S12E5)
9/12/2008
Kim Goldman and Fred Goldman (S12E6)
9/15/2008
Tom Bergeron, Michelle Rodriguez, a 1980s fashion show (S12E7)
9/16/2008
Charlize Theron; Solange Knowles (S12E8)
9/17/2008
Jason Biggs; Dave Stewart (S12E9)
9/18/2008
David Schwimmer; Josh Lucas; Leighton Meester (S12E10)
9/19/2008
Bill Clinton (S12E11)
9/22/2008
Aaron Eckhart, Robert Wagner (S12E12)
9/23/2008
Alec Baldwin (S12E13)
9/24/2008
Chandra Wilson, Emmy look-alikes (S12E14)
9/25/2008
Julianne Moore; Candace Bushnell (S12E15)
9/26/2008
Jennifer Hudson; Selena Gomez; Lisa Ling (S12E16)
9/29/2008
Bill Maher; Kevin Farley, Robert Davi , Dr. Drew Pinsky (S12E17)
9/30/2008
Peter Krause; Diahann Carroll, Miss Piggy (S12E18)
10/1/2008
Greg Kinnear (S12E19)
10/2/2008
Anne Hathaway; Troy Dunn (S12E20)
10/3/2008
Felicity Huffman (S12E21)
10/6/2008
Gretchen Mol; Sarah Silverman (S12E22)
10/7/2008
Dr. Susan Love, Robin Roberts (S12E23)
10/8/2008
Angela Bassett (S12E24)
10/9/2008
Maggie Gyllenhaal, Phil Lempert, Tristan Rogers (S12E25)
10/10/2008
T.I. (S12E26)
10/13/2008
Jim Cramer; Paula Deen; Gabi Wilson (S12E27)
10/14/2008
Tony Curtis; David Alan Grier (S12E28)
10/15/2008
Ashley Hamilton; George Hamilton (S12E29)
10/16/2008
Richard Lewis (S12E30)
10/17/2008
• • • • • • • • • "A Day Of Hot Topics" (S12E31)
10/20/2008
John Lithgow; Eve (S12E32)
10/21/2008
Bill O'Reilly (S12E33)
10/22/2008
Debra Messing (S12E34)
10/23/2008
Kristin Scott Thomas; Sheryl Underwood (S12E35)
10/24/2008
Aretha Franklin (S12E36)
10/27/2008
Duffy; Bridget Regan; Richard Dreyfuss (S12E37)
10/28/2008
Blair Underwood; Natalie Zea; Pink (S12E38)
10/29/2008
Jeremy Piven; Michael Phelps (S12E39)
10/30/2008
Halloween (S12E40)
10/31/2008
Roger Moore (S12E44)
11/6/2008
Ricky Gervais; Mario Cantone; Steve Harvey (S12E45)
11/7/2008
• • • • • • • • • • "A Day Of Hot Topics" (S12E46)
11/10/2008
Alicia Keys; Amy Brenneman (S12E48)
11/12/2008
Season 12, Episode 315 (S12E53)
11/19/2008
Season 12, Episode 316 (S12E54)
11/20/2008
Season 12, Episode 317 (S12E55)
11/21/2008
Season 12, Episode 318 (S12E56)
11/24/2008
Season 12, Episode 319 (S12E57)
11/25/2008
Season 12, Episode 321 (S12E59)
11/27/2008
Season 12, Episode 322 (S12E60)
11/28/2008
Season 12, Episode 337 (S12E75)
12/19/2008
Season 12, Episode 339 (S12E77)
12/23/2008
Season 12, Episode 340 (S12E78)
12/24/2008
Season 12, Episode 341 (S12E79)
12/25/2008
Season 12, Episode 342 (S12E80)
12/26/2008
Season 12, Episode 343 (S12E81)
12/29/2008
Season 12, Episode 344 (S12E82)
12/30/2008
Season 12, Episode 345 (S12E83)
12/31/2008
Season 12, Episode 346 (S12E84)
1/1/2009
Season 12, Episode 347 (S12E85)
1/2/2009
Season 12, Episode 348 (S12E86)
1/5/2009
Season 12, Episode 349 (S12E87)
1/6/2009
Season 12, Episode 350 (S12E88)
1/7/2009
Season 12, Episode 351 (S12E89)
1/8/2009
Season 12, Episode 352 (S12E90)
1/9/2009
Season 12, Episode 353 (S12E91)
1/12/2009
Season 12, Episode 354 (S12E92)
1/13/2009
Season 12, Episode 355 (S12E93)
1/14/2009
Season 12, Episode 356 (S12E94)
1/15/2009
Season 12, Episode 357 (S12E95)
1/16/2009
Season 12, Episode 358 (S12E96)
1/19/2009
Season 12, Episode 359 (S12E97)
1/20/2009
Season 12, Episode 360 (S12E98)
1/21/2009
Season 12, Episode 361 (S12E99)
1/22/2009
Season 12, Episode 362 (S12E100)
1/23/2009
Gov. Rod Blagojevich (S12E101)
1/26/2009
Liza Minnelli, Padma Lakshmi (S12E102)
1/27/2009
Liam Neeson, Jason O'Mara (S12E103)
1/28/2009
Dr. Condoleezza Rice (S12E104)
1/29/2009
Julianne Moore, Whitney Port, Peter Cincotti (S12E105)
1/30/2009
A day of Hot Topics (S12E106)
2/2/2009
Paula Deen, Dev Patel (S12E107)
2/3/2009
Jane Seymour, Amy Dickinson, Richard Jenkins (S12E108)
2/4/2009
Cuba Gooding Jr., Maksim Chmerkovskiy (S12E109)
2/5/2009
Molly Ringwald, Shailene Woodley (S12E110)
2/6/2009
Diane Sawyer, Mario Cantone's Grammy recap (S12E111)
2/9/2009
Joan Rivers, Daniel Dae Kim (S12E112)
2/10/2009
Kate Winslet, Jane Krakowski (S12E113)
2/11/2009
Miss Piggy, Patti Stanger, Helen Fisher (S12E114)
2/12/2009
Clive Owen, Melissa Leo, AIDS expert Jorge Rodriguez (S12E115)
2/13/2009
Patricia Arquette, Emily Osment (S12E116)
2/16/2009
Cast members from Broadway's "Shrek the Musical" (S12E117)
2/17/2009
Bonnie Hunt, Ben Lyons and Ben Mankiewicz (S12E118)
2/18/2009
Laurence Fishburne, Lori Klein (S12E119)
2/19/2009
Tyler Perry, Keshia Knight Pulliam (S12E120)
2/20/2009
Jane Fonda (S12E121)
2/23/2009
Tom Jones (S12E122)
2/24/2009
Jeff Foxworthy, Labelle (S12E123)
2/25/2009
The co-hosts judge their first-ever "Mutt Dog Show" (S12E124)
2/26/2009
Rob Lowe, Jason Mesnick (S12E125)
2/27/2009
A day of Hot Topics (S12E126)
3/2/2009
Marcia Gay Harden (S12E127)
3/3/2009
Dr. Phil McGraw, RuPaul (S12E128)
3/4/2009
Glenn Close, Rachel Maddow (S12E129)
3/5/2009
Jeffrey Dean Morgan, Nathan Fillion (S12E130)
3/6/2009
Miley Cyrus, Jimmy Kimmel (S12E131)
3/9/2009
Jay Leno, Carrie Ann Inaba, Bruno Tonioli, Len Goodman, Lady GaGa (S12E132)
3/10/2009
Patrick Dempsey, Robert Iger (S12E133)
3/11/2009
Kyle MacLachlan, Doug Savant, Maurice Benard (S12E134)
3/12/2009
Sally Field, Calista Flockhart, Heidi Montag and Spencer Pratt (S12E135)
3/13/2009
Jean Chatzky (S12E136)
3/16/2009
Gary Sinise, Dr. Drew Pinsky, Jay Mohr (S12E137)
3/17/2009
Taye Diggs, Ian McShane, Valentino (S12E138)
3/18/2009
Jaime Pressly, Troy Dunn (S12E139)
3/19/2009
Regis Philbin, John Rendall and Ace Bourke (S12E140)
3/20/2009
A day of Hot Topics (S12E141)
3/23/2009
Kevin Bacon, Spencer Grammer, the Bacon Brothers (S12E142)
3/24/2009
Ray Liotta, Kevin McKidd, the Blind Boys of Alabama (S12E143)
3/25/2009
Angela Lansbury, Virginia Madsen, Cheryl Hines (S12E144)
3/26/2009
Susan Sarandon, Geoffrey Rush, Carol Leifer (S12E145)
3/27/2009
Bill O'Reilly, The Dead (S12E146)
3/30/2009
Jonathan Rhys Meyers, Alyssa Milano (S12E147)
3/31/2009
Lauren Graham (S12E148)
4/1/2009
Mary Tyler Moore, Sean Astin, Craig Shoemaker (S12E149)
4/2/2009
Bob Saget, Alexandra Wentworth (S12E150)
4/3/2009
Zac Efron, style expert Lloyd Boston (S12E151)
4/13/2009
How to Get a Job (S12E152)
4/14/2009
Tori Spelling, Bobby Flay (S12E153)
4/15/2009
Tom Bergeron, Kristin Chenoweth (S12E154)
4/16/2009
Matthew Perry, Tracy Pollan (S12E155)
4/17/2009
Dr. Steven Lamm (S12E156)
4/20/2009
Sally Quinn, Quinn Bradlee, Candy Spelling, Suzy Welch, Lily Allen (S12E157)
4/21/2009
Jeremy Irons, the Clark Sisters (S12E158)
4/22/2009
Beyonce, Jim Parsons, guest co-host Meghan McCain (S12E159)
4/23/2009
Lil Wayne, Jamie Luner, guest co-host Meghan McCain (S12E160)
4/24/2009
A day of Hot Topics (S12E161)
4/27/2009
Emily Deschanel, Kim Kardashian, Faith Prince (S12E162)
4/28/2009
Marlee Matlin, Harold Perrineau (S12E163)
4/29/2009
Rick Warren, Ashley Madison CEO Noel Biderman (S12E164)
4/30/2009
Jay Mohr, a performance by the Broadway cast of "9 to 5" (S12E165)
5/1/2009
James Carville, Paul Potts (S12E166)
5/4/2009
Donald Trump, Ivanka Trump, wrestler MVP (S12E167)
5/5/2009
Biz Stone, Evan Williams, Judge Judy Sheindlin, Justin Chambers (S12E168)
5/6/2009
Michael J. Fox, Dr. Nancy Snyderman (S12E169)
5/7/2009
Kenneth Branagh, Leonard Nimoy, Alyse Myers, John Stossel (S12E170)
5/8/2009
Steve Harvey, En Vogue (S12E171)
5/11/2009
Melina Kanakaredes, Maya Rudolph (S12E172)
5/12/2009
Cheryl Saban, Michael Emerson (S12E173)
5/13/2009
Brooke Shields, Neal McDonough (S12E174)
5/14/2009
Tom Hanks, Ayelet Zurer, Ron Howard (S12E175)
5/15/2009
Jesse Ventura (S12E176)
5/18/2009
Elizabeth Edwards (S12E177)
5/19/2009
Glenn Beck (S12E178)
5/20/2009
Larry King, stars of "Southern Belles: Louisville" (S12E179)
5/21/2009
Caroline Manzo, Dina Manzo, Jacqueline Laurita, Sharlene Azam (S12E180)
5/22/2009
Wounded soldiers Melissa Stockwell and Ireshekia Henry, Soulja Boy Tellem (S12E181)
5/25/2009
Faith Prince (S12E182)
5/26/2009
Tyler Florence, Dr. Donnica Moore, The Broadway cast of "Next to Normal" (S12E183)
5/27/2009
David Hyde Pierce, Justin Long, Mellody Hobson (S12E184)
5/28/2009
Nathan Lane, Bill Irwin (S12E185)
5/29/2009
Paris Hilton (S12E186)
6/1/2009
Edie Falco, Nia Vardalos, the Broadway cast of "West Side Story" (S12E187)
6/2/2009
Vanessa Williams, Claire Shipman (S12E188)
6/3/2009
Chandra Wilson, Paula Froelich (S12E189)
6/4/2009
Neil Patrick Harris, Lionel Richie (S12E190)
6/5/2009
Francis Ford Coppola (S12E191)
6/8/2009
Mandy Moore (S12E192)
6/9/2009
Kanye West, Stephen Moyer (S12E193)
6/10/2009
Melissa Gilbert, Joe Scarborough (S12E194)
6/11/2009
Black Eyed Peas (S12E195)
6/12/2009
Wrestler MVP, Dr. Larry Norton (S12E196)
6/15/2009
Jada Pinkett Smith, food stylist Lauren Costello (S12E197)
6/16/2009
Michelle Pfeiffer, Rupert Friend, Shirley Jones, Marty Ingels (S12E198)
6/17/2009
Lauren Conrad, Anne Hathaway (S12E199)
6/18/2009
George Lopez, Mario Cantone, Lewis Black (S12E200)
6/19/2009
Nancy Grace (S12E201)
6/22/2009
Maksim Chmerkovskiy, Benjamin Bratt, Warren Boyd (S12E202)
6/23/2009
Joan Rivers, designer Michael Smith (S12E203)
6/24/2009
Larry David, Evan Rachel Wood, Darius Rucker (S12E204)
6/25/2009
John Edward (S12E205)
6/26/2009
Larry Miller (S12E206)
7/6/2009
Denis Leary, Rob Thomas (S12E207)
7/7/2009
Teri Hatcher, beauty expert Marie Czenko Kuechel (S12E208)
7/8/2009
Margaret Cho, LL Cool J (S12E209)
7/9/2009
Minnie Driver, Tyler Florence (S12E210)
7/10/2009
A day of Hot Topics (S12E211)
7/13/2009
Jimmy Fallon, Kevin Connolly (S12E212)
7/14/2009
Steve Harvey, Daughtry (S12E213)
7/15/2009
Thomas Jane, Jane Adams, Bill Engvall, Dr. Donnica Moore (S12E214)
7/16/2009
Jeff Daniels, Lauren Graham, Tyler Florence (S12E215)
7/17/2009
Charles Gibson (S12E216)
7/20/2009
David Hasselhoff, the Script (S12E217)
7/21/2009
Tyler Florence (S12E218)
7/22/2009
Demi Lovato, Miss USA 2009 Kristen Dalton (S12E219)
7/23/2009
Kevin Spacey (S12E220)
7/24/2009
Mary Jo Buttafuoco (S12E221)
7/27/2009
Jessica Lange, Dr. Gadget (S12E222)
7/28/2009
Ashley Tisdale, Hugh Dancy, Rose Byrne, Dr. Timothy Johnson (S12E223)
7/29/2009
Seth Rogen, Judd Apatow (S12E224)
7/30/2009
Constantine Maroulis, Tyler Florence (S12E225)
7/31/2009
Michelle Malkin (S12E226)
8/3/2009
Eric Bana (S12E227)
8/4/2009
James Brolin, Selena Gomez, David Henrie, Jake T. Austin, the Broadway cast of "Hair" (S12E228)
8/5/2009
Regis Philbin (S12E229)
8/6/2009
Meryl Streep, Amy Adams, Nora Ephron, Lauren Costello (S12E230)
8/7/2009
George Stephanopoulos, Seth Meyers (S12E1103)
11/3/2008
Dennis.Hopper (S12E1104)
11/4/2008
Elton John (S12E1111)
11/11/2008
Alicia.Keys (S12E1112)
11/12/2008
John.Stamos (S12E1113)
11/13/2008
Rachael Ray (S12E1114)
11/14/2008
Hot Topics (S12E1117)
11/17/2008
Jessica Lange (S12E1118)
11/18/2008
Simon Baker (S12E1124)
1/1/0001
Faith Hill (S12E1125)
1/1/0001
Teri Hatcher (S12E1126)
11/26/2008
Nicole Kidman (S12E1128)
11/28/2008
Randy Jackson (S12E1201)
12/1/2008
Patricia Heaton (S12E1202)
12/2/2008
Jeff Goldblum (S12E1203)
12/3/2008
Harry Connick, Jr (S12E1204)
12/4/2008
Hugh Jackman (S12E1205)
12/5/2008
Paula Abdul (S12E1208)
12/8/2008
Don Rickles (S12E1209)
12/9/2008
Day of Hot Topics (S12E1210)
12/10/2008
Dr. Mehmet Oz (S12E1211)
12/11/2008
Meryl Streep (S12E1212)
12/12/2008
Keri Russell (S12E1215)
12/15/2008
Samuel L. Jackson (S12E1216)
12/16/2008
Hot Topics (S12E1217)
12/17/2008
Michael Bloomberg (S12E1218)
12/18/2008
Comedy Theme Show (S12E1222)
12/22/2008
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