Overview: After the death of Julius Caesar, Cleopatra needed a new political ally in Rome. With her life, her son's life, and the fate of Egypt hanging in the balance, she set her sights on the new co-ruler of the Roman Empire: Mark Antony. Their romance would become the ancient world's greatest love story and darkest tragedy. See how their relationship grew from a calculated political move to a passionate affair before devolving into a catastrophic tale of betrayal, murder, and suicide.