John Oliver, Quinta Brunson, Courtney Barnett (S10E1)
9/20/2022
Ana de Armas, Reba McEntire, Ms. Pat (S10E2)
9/21/2022
Billy Eichner, Beth Ditto (S10E3)
9/22/2022
Alan Cumming, Bobby Moynihan (S10E4)
9/23/2022
Senator Bernie Sanders, Chad Kroeger & JT Parr (S10E5)
9/27/2022
Nick Kroll, Steve-O, Dick Ebersol (S10E6)
9/28/2022
Timothy Olyphant, Rachel Sennott (S10E7)
9/29/2022
Colin Jost, Paul Mescal, 5 Seconds of Summer (S10E8)
9/30/2022
Constance Wu, Ramy Youssef (S10E9)
10/4/2022
Queen Latifah, Sarah Sherman, Celeste Ng (S10E10)
10/5/2022
Kelly Ripa, Fred Armisen, Ana Fabrega and Julio Torres, Ashley McBryde (S10E11)
10/6/2022
Hasan Minhaj, Tony Hale (S10E12)
10/7/2022
Vice President Kamala Harris, Geena Davis (S10E13)
10/11/2022
Brendan Gleeson & Colin Farrell, Kaitlyn Dever (S10E14)
10/12/2022
Pierce Brosnan, Sharon Horgan, Craig Finn & The Uptown Controllers (S10E15)
10/13/2022
Johnny Knoxville, Jake Lacy, Pusha T (S10E16)
10/14/2022
Ice T, John Irving, Rina Sawayama (S10E17)
11/1/2022
Jake Tapper, Sheryl Lee Ralph, Sohla El-Waylly (S10E18)
11/2/2022
Daniel Radcliffe & Weird Al Yankovic, Kerry Condon, Kurt Vile & The Violators (S10E19)
11/3/2022
Cecily Strong, Evan Rachel Wood (S10E20)
11/4/2022
Gayle King, Bobby Cannavale (S10E21)
11/8/2022
Florence Pugh, Steve Kornacki (S10E22)
11/10/2022
Tracy Morgan, James Acaster (S10E23)
11/11/2022
Chelsea Handler, Martin McDonagh (S10E24)
11/15/2022
Quentin Tarantino, Emily Ratajkowski, Seth Reiss & Will Tracy (S10E25)
11/16/2022
John Leguizamo, Zoe Kazan, Paolo Nutini (S10E26)
11/17/2022
David Duchovny, Sarah Jones (S10E27)
11/18/2022
Jim Parsons, Amber Ruffin & Lacey Lamar (S10E28)
11/22/2022
Kumail Nanjiani, Matt Rogers, A Performance from the Cast of Titanique (S10E29)
11/23/2022
Bruce Springsteen, Mike Birbiglia (S10E30)
11/24/2022
Hilary, Larry and Josh Meyers (S10E31)
11/25/2022
Lea Michele, Janelle James (S10E32)
12/6/2022
Chris Hayes, Charlotte Nicdao (S10E33)
12/7/2022
Jesse Eisenberg, Meghann Fahy (S10E34)
12/8/2022
Catherine Zeta-Jones, Hong Chau (S10E35)
12/9/2022
Aubrey Plaza, Bashir Salahuddin & Diallo Riddle (S10E36)
12/13/2022
Kate Hudson, Angie Rito & Scott Tacinelli (S10E37)
12/14/2022
Janelle Monáe, Paul Dano (S10E38)
12/15/2022
Paul Bettany, Lily Collins (S10E39)
12/16/2022
Michael Shannon, Danielle Brooks (S10E40)
1/4/2023
Brendan Fraser, Roy Wood Jr. (S10E41)
1/5/2023
Jordan Peele, Melissa Rauch (S10E42)
1/6/2023
Allison Williams, S.S. Rajamouli (S10E43)
1/10/2023
Tom Hanks, Jessie Buckley, Stephen Markley (S10E44)
1/11/2023
Gerard Butler, Nico Parker, Inhaler (S10E45)
1/12/2023
Anna Kendrick, John Larroquette (S10E46)
1/13/2023
Leslie Jones, Rosie Perez (S10E47)
1/17/2023
Common, Jonathan Lemire, A Performance from Some Like It Hot (S10E48)
1/18/2023
George Lopez, Sadie Sink (S10E49)
1/19/2023
Kenan Thompson, Jinkx Monsoon (S10E50)
1/20/2023
Hilary Duff, Kim Petras (S10E51)
1/24/2023
Ana Gasteyer, Bomani Jones, Sam Morrison (S10E52)
1/25/2023
Colin Quinn, Gabrielle Union (S10E53)
1/26/2023
Alex Wagner, Bowen Yang (S10E54)
1/27/2023
Christopher Meloni, D'Arcy Carden (S10E55)
1/31/2023
Terry Crews, Rupert Grint, Rian Johnson (S10E56)
2/1/2023
Natasha Lyonne, Adam Pally (S10E57)
2/2/2023
Alan Cumming, Jonathan Groff (S10E58)
2/3/2023
Taylor Schilling, Eddie Izzard (S10E59)
2/7/2023
Reese Witherspoon, Paula Pell, Chef Michael Solomonov (S10E60)
2/8/2023
Judd Hirsch, Justice Smith, Regina Spektor (S10E61)
2/9/2023
Fred Armisen, Penn Badgley (S10E62)
2/10/2023
David Harbour, Kathryn Newton (S10E63)
2/14/2023
Paul Rudd (S10E64)
2/15/2023
Pedro Pascal, Taye Diggs (S10E65)
2/16/2023
Tina Fey, Nate Bargatze (S10E66)
2/17/2023
Woody Harrelson, Niall Horan (S10E67)
2/28/2023
Rachel Brosnahan, Matthew Rhys, Francia Raisa (S10E68)
3/1/2023
Jim Gaffigan, Richard Kind (S10E69)
3/2/2023
Jonathan Majors, Riley Keough (S10E70)
3/3/2023
Hank Azaria, Diane Morgan (S10E71)
3/7/2023
Ike Barinholtz, Melissa Barrera, Margaret Atwood (S10E72)
3/8/2023
Nick Kroll, Zoe Chao, Zara Larsson (S10E73)
3/9/2023
Adam Driver, Adam Brody (S10E74)
3/10/2023
John Oliver (S10E75)
3/14/2023
James Spader, Ian McShane, Ms. Pat (S10E76)
3/15/2023
Bryan Cranston, Nicole Byer, keshi (S10E77)
3/16/2023
Jason Sudeikis, Annaleigh Ashford (S10E78)
3/17/2023
Jeff Goldblum, Jeff Goldblum & The Mildred Snitzer Orchestra (S10E79)
3/28/2023
Andy Samberg, Chris O'Dowd (S10E80)
3/29/2023
Adam Scott, Jeff Tweedy, Wilco (S10E81)
3/30/2023
Taron Egerton, Maude Apatow, Jessi Klein (S10E82)
3/31/2023
Rob Lowe & John Owen Lowe, Judd Winick, Ruston Kelly (S10E83)
4/4/2023
Jason Bateman, Rep. Alexandria Ocasio-Cortez (S10E84)
4/5/2023
Chris Pratt, Ali Wong, The Hold Steady (S10E85)
4/6/2023
Matt Damon, Kristin Chenoweth (S10E86)
4/7/2023
Laura Dern, Miranda Lambert (S10E87)
4/25/2023
Nathan Lane, Rep. Katie Porter, A Performance from the Cast of & Juliet (S10E88)
4/26/2023
Keri Russell, Graham Norton (S10E89)
4/27/2023
Amy Poehler, Lucinda Williams (S10E90)
4/28/2023
Chance the Rapper, Parker Posey (S10E91)
5/2/2023
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