Overview: Comedy masters, Jeffrey Tambor (Transparent), Aziz Ansari (Master of None), Anthony Anderson (Black-ish), Tony Hale (Veep), Jerrod Carmichael (The Carmichael Show), Rob Lowe (The Grinder), Keegan-Michael Key (Key & Peele), divulge their most embarrassing moments, who inspires them and the challenges of taking a comedic look at serious topics.